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Ryan Reynolds filmed his colonoscopy after losing a bet—it turned out to be ‘lifesaving’

Cancer is serious. Ryan Reynolds is not. Luckily his characteristic sense of humor—along with being true to his word—has helped shine a light on a sobering topic in a fun way.

After apparently losing a bet to friend and “Welcome to Wrexham” co-star Rob McElhenney of “It’s Always Sunny in Philadelphia,” Reynolds agreed to get a colonoscopy … while broadcasting it to the entire world, of course.

Reynolds is an actor famous for hilarious hijinks. From his intense fictional feud with Hugh Jackman to performing epic pranks on talk shows, he is often the best thing on the internet for a good laugh.

However, he is also not one to shy away from difficult conversations, particularly when it comes to health. So raising awareness about the importance of colonoscopies was, as he quipped, “enough motivation for me to let you in on a camera being shoved up my ass.”

Reynolds might have lost the bet, but his actions paid off. The procedure turned out to be lifesaving.


The video shows the “Free Guy” actor getting the news that an “extremely subtle” polyp was discovered and cut out. Reynolds had previously shown no symptoms.

“I’m not being dramatic,” his doctor told him. “This is exactly why you do this. You are interrupting the natural history of a disease, of something of a process that could have ended up developing into cancer and causing all sorts of problems. Instead, you are not only diagnosing the polyp, you are taking it out.”

Ever the expert marketer, Reynolds smoothly slid in a quick plug for his alcohol brand, joking that “I can’t believe you pumped all that Aviation Gin into my IV. I was out like a light” before thanking the doctor.

Reynolds got his colonoscopy at 45, which is the recommended age to begin routine screenings. Though it’s a preventable cancer, colorectal cancer is the third most common cause of cancer-related deaths for men and women combined, and it is predicted to be the top cancer killer for people under 50 by the year 2030.

Because of the inherent invasiveness of the procedure, many people feel uncomfortable even talking about colonoscopies, let alone getting one, despite early detection being so vital. But now, thanks to Reynolds hilariously riffing on his experience, the whole thing might not seem so daunting after all.

Thanks for the delightfully silly PSA, Ryan.